NCIt definition : The bromide form of azoximer, a N-oxidized polyethylene-piperazine derivative and
a heterochain aliphatic polyamine, with potential immunomodulating and immunoadjuvant
activities. Upon administration, azoximer binds to and induces the activation of myeloid
cells, mostly monocytes and neutrophils, and, to a lesser extent, lymphocytes. Azoximer
increases the expansion of immature DC (iDC) and mature DC (mDC) at inflammatory sites,
stimulates expression of several DC co-stimulatory molecules, and induces the proliferation
and recruitment of T-cells to inflammatory or tumor sites. Azoximer also enhances
intracellular hydrogen peroxide (H2O2) production.;
UNII : 90G53638ZD;
CAS number : 892497-01-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 892497-01-7
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