Azoximer Bromide

Preferred Label : Azoximer Bromide;

NCIt synonyms : Polyoxidonium (TM);

NCIt definition : The bromide form of azoximer, a N-oxidized polyethylene-piperazine derivative and a heterochain aliphatic polyamine, with potential immunomodulating and immunoadjuvant activities. Upon administration, azoximer binds to and induces the activation of myeloid cells, mostly monocytes and neutrophils, and, to a lesser extent, lymphocytes. Azoximer increases the expansion of immature DC (iDC) and mature DC (mDC) at inflammatory sites, stimulates expression of several DC co-stimulatory molecules, and induces the proliferation and recruitment of T-cells to inflammatory or tumor sites. Azoximer also enhances intracellular hydrogen peroxide (H2O2) production.;

UNII : 90G53638ZD;

CAS number : 892497-01-7;

Details

Origin ID

C171819;

UMLS CUI

C5383285;

Automatic exact mappings (from CISMeF team)
- azoximer bromide [MeSH concept]
- azoximer bromide [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- azoximer bromide [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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