" /> Lintuzumab - CISMeF





Preferred Label : Lintuzumab;

NCIt synonyms : monoclonal antibody HuM195 HuG1-M195; MoAb HuM195; Hu-M195 monoclonal antibody; HuG1-M195 monoclonal antibody; Monoclonal Antibody HuM195; MoAb HuG1-M195; Monoclonal Antibody HuG1-M195; SMART M195; Humanized M195;

NCIt definition : A humanized recombinant monoclonal antibody directed against CD33, a cell surface antigen found on myeloid leukemia blasts and early hematopoietic progenitor cells. Lintuzumab stimulates antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing CD33, resulting in a decrease in tumor burden. The humanized version of this monoclonal antibody exhibits less immunogenicity and improved binding affinity compared to its murine counterpart.;

Alternative definition : NCI-GLOSS: A substance being studied in the treatment of myelodysplastic syndromes and some types of leukemia. It binds to CD33, a protein on the surface of certain normal blood stem cells and some abnormal blood cells. It causes the immune system to kill these cells. Lintuzumab is a type of monoclonal antibody.;

UNII : V00Y10W60W;

CAS number : 166089-32-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 166089-32-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Zamyl;

Molecule name : SGN-33;

Codes from synonyms : CDR0000661993; CDR0000661991;

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15/05/2024


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