Preferred Label : Cationic Peptide Cream Cypep-1;
NCIt definition : A topical cream containing Cypep-1, a cationic lytic peptide of 27 amino acids, with
potential antineoplastic activity. Upon topical administration, Cypep-1 selectively
targets tumor cells with negatively charged cell membranes and ruptures the cell membranes.
This leads to tumor cell lysis and the release of neoantigens into the tumor microenvironment
(TME) and circulation. This elicits a specific and potent cytotoxic T-lymphocyte (CTL)
response against tumor cells expressing these neoantigens. Warts are benign skin tumors
caused by human papilloma virus (HPV).;
Molecule name : Cypep-1;
NCI Metathesaurus CUI : CL1405490;
Origin ID : C171374;
UMLS CUI : C5417856;
Semantic type(s)
- concept_is_in_subset
