Preferred Label : Pentetic Acid Calcium;
Obsolete resource : true;
NCIt synonyms : Calcium-DTPA; Calcium Pentetic Acid; Calcium DTPA; Ca-DTPA;
NCIt definition : The calcium salt of pentetic acid, a synthetic chelating agent related to the chelating
agent ethylenediaminetetraacetic acid (EDTA). Pentetic acid chelates with the metallic
radioisotopic moieties of unbound, extracellular radioimmunotherapeutic agents, resulting
in higher specific tumor cell binding of radioimmunotherapeutic agents; this results
in improved tumor cell radiocytotoxicity and the sparing of normal cells and tissues
from the radiocytotoxic effects of these agents.;
Alternative definition : NCI-GLOSS: A drug that protects healthy tissues from the toxic effects of anticancer
drugs.;
NCIt note : See 'Pentetate Calcium(C120569)';
Concept status : Retired_Concept;
CAS number : 2531-75-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2531-75-1
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G-SRS /a ;
Codes from synonyms : CDR0000045514;
Origin ID : C1710;
UMLS CUI : C4048602;
See also inter- (CISMeF)
- Semantic type(s)
