NCIt definition : An orally available, small molecule inhibitor of human respiratory syncytial virus
(RSV) fusion protein (F protein), with potential antiviral activity. Upon oral administration,
sisunatovir specifically targets and binds to RSV-F protein on the viral surface,
which inhibits RSV-F protein-mediated fusion with the host cell membrane and prevents
viral entry. This blocks RSV replication, reduces viral load, and decreases the severity
of the disease. RSV-F protein, a viral surface glycoprotein, plays a key role in RSV
fusion with and entry into target cells.;
Currated CISMeF NLP mapping