Preferred Label : Levofloxacin Anhydrous;
NCIt synonyms : 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic Acid, 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-,
(S)-; (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic
Acid;
NCIt definition : The anhydrous form of levofloxacin, a broad-spectrum, third-generation fluoroquinolone
antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.
Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase
(bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription,
and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of
bacterial cell growth.;
UNII : RIX4E89Y14;
InChIKey : GSDSWSVVBLHKDQ-JTQLQIEISA-N;
CAS number : 100986-85-4;
Chemical formula : C18H20FN3O4;
NCI Metathesaurus CUI : CL1382974;
Origin ID : C170539;
UMLS CUI : C3661457;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
