" /> Tanomastat - CISMeF





Preferred Label : Tanomastat;

NCIt synonyms : (S)-3-[(4'-Chloro-4-biphenylyl)carbonyl]-2-[(phenylthio)methyl]propionic acid; 4-[4-(chlorophenyl)phenyl]-4-oxo-2S-(phenylthiomethyl) butanoic acid;

NCIt related terms : BAY 12-9566;

NCIt definition : A biphenyl matrix metalloproteinase (MMP) inhibitor (MMPI) with potential antineoplastic activity. Tanomastat inhibits MMP-2, MMP-3, and MMP-9, inhibiting extracellular matrix degradation and potentially inhibiting angiogenesis, tumor growth and invasion, and metastasis. MMPs consist of at least 18 zinc-containing endo-proteinases that are capable of degrading collagen and proteoglycan.;

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors.;

UNII : AM1ZX94EXH;

InChIKey : JXAGDPXECXQWBC-LJQANCHMSA-N;

CAS number : 179545-77-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 179545-77-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : BAY-12-9566; BAY 12-9566;

Chemical formula : C23H19ClO3S;

Codes from synonyms : 31642; CDR0000045539;

PubMed : 16442153;

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12/05/2024


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