Preferred Label : Pegloprastide;
NCIt synonyms : Fluorescent Protease-activated Peptide AVB-620;
NCIt definition : A protease-cleavable peptide linked to a fluorescent probe, with potential imaging
activity. Upon intravenous infusion of pegloprastidebefore surgery, the peptide moiety
of AVB-620 can be cleaved by proteases overexpressed by tumor cells. This activates
the fluorescent probe and the tumor cells expressing the prote ases can be detected
using a fluorescence imaging system. This allows for the visualization and removal
of the tumor during surgery.;
UNII : U6M486P0QJ;
CAS number : 2138471-65-3;
Molecule name : AVB-620;
NCI Metathesaurus CUI : CL1382542;
Origin ID : C170299;
UMLS CUI : C5418503;
Semantic type(s)
- concept_is_in_subset
