" /> Proto-Oncogene - CISMeF





Preferred Label : Proto-Oncogene;

NCIt synonyms : Cellular Oncogene; c-ONC; Cellular Oncogenes;

NCIt definition : Oncogenes are altered forms of normal cellular genes called proto-oncogene. Many proto-oncogenes are homologous to viral oncogenes and involved in the control of cell proliferation or differentiation. Mutations, amplifications or rearrangements of proto-oncogenes lead to upregulated or deregulated cell growth and allow them to function as oncogenes.;

Alternative definition : NCI-GLOSS: A gene involved in normal cell growth. Mutations (changes) in a proto-oncogene may cause it to become an oncogene, which can cause the growth of cancer cells.;

Codes from synonyms : CDR0000641134;

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08/05/2025


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