Netarsudil - CISMeF

Preferred Label : Netarsudil;

NCIt definition : An amino-isoquinoline amide and inhibitor of Rho kinase (ROCK) and norepinephrine transporter (NET), with potential intraocular pressure (IOP)-lowering activity. Upon ocular administration, netarsudil inhibits ROCK and the Rho pathway, increases aqueous humor (AH) outflow via the trabecular pathway, and lowers IOP. In addition, netarsudil may lower IOP by decreasing episcleral venous pressure and decreasing the production of aqueous humor through inhibition of NET.;

UNII : W6I5QDT7QI;

InChIKey : OURRXQUGYQRVML-AREMUKBSSA-N;

CAS number : 1254032-66-0;

NCI Metathesaurus CUI : CL1382686;

Details

Origin ID

C170213;

UMLS CUI

C4535718;

Currated CISMeF NLP mapping
- Netarsudil [ICD-11 Extension code]
- Netarsudil [SMS substance]
- Netarsudil (substance) [SNOMED CT concept]
- netarsudil [MeSH concept]
- netarsudil [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Netarsudil (substance) [SNOMED CT concept]
- Product containing netarsudil (medicinal product) [SNOMED CT concept]
- netarsudil [MeSH Supplementary Concept]
- netarsudil [ATC Code]
Validated automatic mappings to BTNT
- netarsudil [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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