Metreleptin - CISMeF

Preferred Label : Metreleptin;

NCIt synonyms : N-Methionylleptin;

NCIt definition : A recombinant human leptin analog composed of human leptin with the addition of a methionine residue at its amino terminus, that may be used for the treatment of leptin deficiency. Upon administration, metreleptin binds to and activates the human leptin receptor (ObR). This activates leptin/ObR-mediated signaling pathways. Leptin, a hormone predominantly secreted by adipose tissue, plays an important role in maintaining energy homeostasis.;

UNII : TL60C27RLH;

CAS number : 186018-45-1;

Drug name : Myalept;

NCI Metathesaurus CUI : CL1382664;

Details

Origin ID

C170171;

UMLS CUI

C0961965;

Currated CISMeF NLP mapping
- Metreleptin [SMS substance]
- Metreleptin (substance) [SNOMED CT concept]
- metreleptin [MeSH Supplementary Concept]
- metreleptin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Metreleptin (substance) [SNOMED CT concept]
- Product containing metreleptin (medicinal product) [SNOMED CT concept]
- metreleptin [MeSH Supplementary Concept]
- metreleptin [MeSH concept]
- metreleptin [ATC Code]
Validated automatic mappings to BTNT
- metreleptin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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