" /> Cabotegravir - CISMeF





Preferred Label : Cabotegravir;

NCIt definition : A human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI), that is used for pre-exposure prophylaxis (PrEP) to reduce the risk of sexually acquired HIV-1 infection. Upon gluteal intramuscular administration, cabotegravir binds to the active site of HIV integrase and inhibits the activity of HIV integrase, an HIV-1 coded enzyme that is necessary for viral replication. Inhibition of integrase prevents the integration of HIV-1 DNA into host genomic DNA.;

UNII : HMH0132Z1Q;

InChIKey : WCWSTNLSLKSJPK-LKFCYVNXSA-N;

CAS number : 1051375-10-0;

Drug name : Apretude;

NCI Metathesaurus CUI : CL601825;

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27/07/2025


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