NCIt definition : A mimetic of the enzyme superoxide dismutase (SOD) that may potentially be used to
reduce oral mucositis and esophagitis associated with radiation therapy and chemoradiotherapy.
Upon administration, avasopasem manganese may mimic native SODs and catalyze the formation
of molecular oxygen and hydrogen peroxide from the burst of superoxide anion present
in the irradiated tissues upon radiation and/or induced by chemotherapy. This may
decrease the damage of radiation and/or chemotherapy to normal tissues.;