Recombinant Interleukin-17

Preferred Label : Recombinant Interleukin-17;

NCIt synonyms : CTLA-8 (Therapeutic); Interleukin-17; IL-17; Therapeutic Interleukin-17;

NCIt definition : A recombinant agent, which is chemically identical or similar to the endogenous cytokine interleukin-17 (IL-17). IL-17 is produced by cytotoxic T cells and stimulates stromal cells to produce pro-inflammatory and hematopoietic cytokines. This cytokine enhances expression of IL-6, IL-8, and ICAM-1 in fibroblasts and appears to induce osteoclastogenesis.;

Details

Origin ID

C1684;

UMLS CUI

C1522571;

Currated CISMeF NLP mapping
- Interleukin-17 [FMA entity]
- Interleukin-17 [MeSH concept]
- interleukin 17 [COVID-19 Thesaurus concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
Validated automatic mappings to NTBT
- Interleukin-17 [MeSH Descriptor]
chemical_or_drug_has_physiologic_effect
- Inhibition of Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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