Preferred Label : Modified Vaccinia Ankara-vectored HPV16/18 Vaccine JNJ-65195208;
NCIt synonyms : MVA-vectored HPV16/18 Vaccine JNJ-65195208; Modified Vaccinia Ankara-HPV16/18 JNJ-65195208; MVA.HPV16/18 JNJ-65195208; MVA BN HPV16/18 JNJ-65195208; MVA-HPV16/18 Vaccine JNJ-65195208; MVA-vectored Vaccine JNJ-65195208;
NCIt definition : A booster cancer vaccine comprised of a modified, replication-defective, vaccinia
virus Ankara (MVA) Bavarian Nordic (MVA-BN) strain encoding the oncogenic human papillomavirus
types 16 (HPV16) and 18 (HPV18), with potential immunostimulating and antineoplastic
activities. Upon intramuscular administration of MVA-vectored HPV16/18 vaccine JNJ-65195208,
and after the administration of the prime vaccine(s) adenovirus serotype 26 (Ad26)-expressing
HPV16 vaccine JNJ-63682918 and/or Ad26-expressing HPV18 vaccine JNJ-63682931, this
vaccine further stimulates the host immune system to mount a cytotoxic T-lymphocyte
(CTL) response against tumor cells expressing HPV16/18 proteins, resulting in tumor
cell lysis. HPV16/18 infection plays a key role in the development of a variety of
cancers.;
Molecule name : JNJ-65195208; JNJ 65195208;
NCI Metathesaurus CUI : CL972336;
Origin ID : C167362;
UMLS CUI : C5238493;
Semantic type(s)
- concept_is_in_subset
