Preferred Label : Adenovirus Serotype 26-expressing HPV16 Vaccine JNJ-63682918;
NCIt synonyms : Ad26-expressing HPV16 Vaccine JNJ-63682918; Monovalent HPV16 Ad26-vectored Vaccine JNJ-63682918; Adenovirus Serotype 26-Human Papillomavirus 16 JNJ-63682918; Ad26.HPV16 JNJ-63682918;
NCIt definition : A prime cancer vaccine comprised of a genetically engineered, replication-deficient
adenovirus serotype 26 (Ad26) encoding the oncogenic human papillomavirus 16 (HPV16),
with potential immunostimulating and antineoplastic activities. Upon intramuscular
administration of Ad26-expressing HPV16 vaccine JNJ-63682918, the adenovirus infects
and expresses HPV16. The expressed proteins stimulate the host immune system to mount
a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing HPV16 antigens,
thereby inducing tumor cell lysis. HPV16 infection plays a key role in the development
of a variety of cancers.;
Molecule name : JNJ-63682918; JNJ 63682918;
NCI Metathesaurus CUI : CL972334;
Origin ID : C167360;
UMLS CUI : C5238491;
Semantic type(s)
- concept_is_in_subset
- has_target
