Activating ERBB2 Point Mutation

Preferred Label : Activating ERBB2 Point Mutation;

NCIt synonyms : Activating HER2 Point Mutation; ERBB2 Activating Point Mutation; HER2/Neu Activating Point Mutation; CD340 Activating Point Mutation; Activating ERBB2 Gene Point Mutation; HER-2 Activating Point Mutation; c-erbB2 Activating Point Mutation; HER2 Activating Point Mutation;

NCIt definition : A point mutation in the nucleotide sequence of the ERBB2 gene that that results in constitutive receptor tyrosine-protein kinase erbB-2-dependent signal transduction and activation of downstream signaling pathways.;

NCI Metathesaurus CUI : CL972381;

Details

Origin ID

C167151;

UMLS CUI

C5238312;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
molecular_abnormality_involves_gene
- ERBB2 Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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