Hypoxanthine Phosphoribosyltransferase

Preferred Label : Hypoxanthine Phosphoribosyltransferase;

Obsolete resource : true;

NCIt synonyms : EC 2.4.2.8; HPRT;

NCIt definition : Cytoplasmic Hypoxanthine Phosphoribosyltransferases (Purine/Pyrimidine Phosphoribosyltransferase Family) catalyze the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or 6-mercaptopurine to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. (NCI);

NCIt note : Wed Sep 05 16:17:39 EDT 2012 - Unnecessary header.; Protein_Plays_Role_In_Biological_Process: Purine Salvage;

Concept status : Retired_Concept;

Details

Origin ID

C16703;

UMLS CUI

C0020687;

Automatic exact mappings (from CISMeF team)
- PRTFDC1 protein, human [MeSH Supplementary Concept]
- estrone sulfotransferase [MeSH Supplementary Concept]
- heparitinsulfate lyase [MeSH Supplementary Concept]
- hypoxanthine phosphoribosyltransferase 1 [ORDO Gene]
- hypoxanthine phosphoribosyltransferase activity [GO term]
Currated CISMeF NLP mapping
- Hypoxanthine phosphoribosyltransferase [LOINC component]
- hypoxanthine phosphoribosyltransferase [MeSH Descriptor]
- hypoxanthine phosphoribosyltransferase [MeSH concept]
- hypoxanthine phosphoribosyltransferase [SNOMED Notion]
False automatic mappings
- Hypoxanthine phosphoribosyltransferase (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Hypoxanthine phosphoribosyltransferase [LOINC component]
- Hypoxanthine phosphoribosyltransferase (substance) [SNOMED CT concept]
- hypoxanthine phosphoribosyltransferase [MeSH Descriptor]
- hypoxanthine phosphoribosyltransferase [MeSH concept]
- hypoxanthine phosphoribosyltransferase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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