" /> Ibandronate Sodium - CISMeF





Preferred Label : Ibandronate Sodium;

NCIt related terms : ibandronate;

NCIt definition : The sodium salt form of ibandronic acid, a synthetic nitrogen-containing bisphosphonate. Ibandronic acid inhibits farnesyl pyrophosphate synthase, resulting in a reduction in geranylgeranyl GTPase signaling proteins and apoptosis of osteoclasts. This agent increases bone mineral density, decreases bone remodeling, inhibits osteoclast-mediated bone resorption, and reduces metastases-related and corticosteroid-related bone pain.;

Alternative definition : NCI-GLOSS: A drug that is used to prevent and treat osteoporosis, and is being studied in the treatment of cancer that has spread to the bones. It belongs to the family of drugs called bisphosphonates.;

UNII : J12U072QL0;

InChIKey : VBDRTGFACFYFCT-UHFFFAOYSA-M;

CAS number : 138926-19-9;

Drug name : Bondronate; Boniva;

Chemical formula : C9H22NO7P2.Na.H2O;

Codes from synonyms : CDR0000377709; 20612;

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11/05/2025


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