Preferred Label : Uniformly-labeled [13C]lactate;
NCIt synonyms : [U-13C]lactate; U-13C-Lactate;
NCIt definition : A uniformly-labeled radioconjugate composed of lactate in which all three carbons
are labeled with the isotope carbon C 13 (13C), with potential imaging application.
Upon administration of uniformly-labeled [13C]lactate, lactate is taken up and metabolized
by tumors, via the tricarboxylic acid (TCA) cycle, and the 13C-containing metabolites
can be imaged by 13C nuclear magnetic resonance (NMR) spectroscopy. As certain tumor
cells preferentially take up and metabolize lactate for fuel, this agent may help
assess the extent of lactate metabolism in tumor cells.;
NCI Metathesaurus CUI : CL971653;
Origin ID : C166401;
UMLS CUI : C5237958;
Semantic type(s)
- concept_is_in_subset
