Recombinant Interferon-alpha Inducible Protein 10

Preferred Label : Recombinant Interferon-alpha Inducible Protein 10;

NCIt synonyms : IP 10; CXCL10; Interferon-gamma Inducible Protein 10; Therapeutic Interferon-alpha Inducible Protein 10;

NCIt definition : A recombinant agent, chemically identical or similar to the endogenous small inducible cytokine B10 (IP-10). Interferon-alpha inducible protein 10 is secreted from macrophages, endothelial cells, and keratinocytes in response to stimulation of IFN-gamma. This agent is a potent inhibitor of angiogenesis, bone marrow colony formation, and is a chemoattractant for monocytes and T-cells, promotes T-cell adhesion to endothelial cells, and probably participates in chronic cell-mediated inflammatory reactions.;

Details

Origin ID

C1664;

UMLS CUI

C1522712;

Automatic exact mappings (from CISMeF team)
- 5(4'-hydroxybenzylidenoimino)-3-methylisothiazolo(5,4-d)pyrimidine-(7H)-4,6-dione [MeSH Supplementary Concept]
- Chemokine, cxc motif, ligand 10 [OMIM gene]
- chemokine cxcl10 [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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