NCIt definition : A murine immunoglobulin G1 (IgG1) monoclonal antibody directed against the CD37 antigen
with potential antineoplastic activity. Upon administration, lilotomab both activates
the immune system to induce an antibody-dependent cell-mediated cytotoxicity (ADCC)
against CD37-overexpressing tumor cells and induces apoptosis in these tumor cells.
CD37 is a transmembrane glycoprotein expressed at high-levels on B-cells and to a
lesser extent on T-cells and myeloid cells, and is frequently overexpressed in certain
B-cell malignancies.;
UNII : 58I6YNR7BV;
CAS number : 1453362-55-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1453362-55-4
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G-SRS /a ;
Semantic type(s)