Pigmented Epithelioid Melanocytoma

Preferred Label : Pigmented Epithelioid Melanocytoma;

NCIt synonyms : Epithelioid Blue Nevus; PEM;

NCIt definition : A rare cutaneous melanocytic neoplasm that presents as a slow growing pigmented nodule or papule. It is characterized by the proliferation of heavily pigmented epithelioid and dendritic cells, predominantly in the dermis. PRKAR1A gene inactivation is present in the majority of cases. It can spread to regional lymph nodes, but distant metastases are rare.;

Neoplastic status : Undetermined;

NCI Metathesaurus CUI : CL978566;

Details

Origin ID

C165498;

UMLS CUI

C5230531;

Automatic exact mappings (from CISMeF team)
- Extramedullary soft tissue plasmacytoma [ORDO Disease]
- Mucin 1, cell surface associated [OMIM gene]
- Pigmented epithelioid melanocytoma [ICD-11 Extension code]
- evoked potentials, motor [MeSH Descriptor]
- mucin 1, cell surface associated [ORDO Gene]
Currated CISMeF NLP mapping
- Pigmented epithelioid melanocytoma [MedDRA Preferred Term]
Disease may have findings
- HMB-45-Positive Neoplastic Cells Present [NCIt concept]
- S-100-Positive Neoplastic Cells Present [NCIt concept]
Has associated anatomic sites
- Integumentary System [NCIt concept]
- Skin [NCIt concept]
See also inter- (CISMeF)
- Pigmented epithelioid melanocytoma (morphologic abnormality) [SNOMED CT concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Pigmented epithelioid melanocytoma [MedDRA Preferred Term]
- Pigmented epithelioid melanocytoma (morphologic abnormality) [SNOMED CT concept]
concept_is_in_subset
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
disease_has_abnormal_cell
- Epithelioid Melanocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Melanocyte [NCIt concept]
disease_has_finding
- Cutaneous Involvement [NCIt concept]
- Darkly Pigmented Melanophages Present [NCIt concept]
- Melanin-Pigmented Dendritic Cells Present [NCIt concept]
- Melanin-Pigmented Epithelioid Cells Present [NCIt concept]
disease_has_normal_cell_origin
- Melanocyte [NCIt concept]
disease_has_normal_tissue_origin
- Skin Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Skin [NCIt concept]
disease_may_have_associated_disease
- Carney Complex [NCIt concept]
may_be_associated_disease_of_disease
- Carney Complex [NCIt concept]

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