NCIt synonyms : Respiratory Syncytial Virus Fusion Protein Inhibitor JNJ-53718678; RSV F Protein Inhibitor JNJ-53718678; RSV Fusion Protein Inhibitor JNJ-53718678;
NCIt definition : An orally available inhibitor of human respiratory syncytial virus (RSV) fusion protein
(F protein), with potential antiviral activity. Upon oral administration, rilematovir
specifically targets and binds to F protein on the viral surface, which inhibits RSV
F protein-mediated fusion with the host cell membrane and prevents viral entry. This
blocks RSV replication, reduces viral load, and decreases the severity of the disease.
RSV F protein, a viral surface glycoprotein, plays a key role in RSV fusion with and
entry into target cells.;
UNII : NQ99E8OH3P;
InChIKey : GTQTUABHRCWVLL-UHFFFAOYSA-N;
CAS number : 1383450-81-4;
Molecule name : JNJ-678; JNJ-53718678; JNJ-8678; JNJ 53718678;
See also inter- (CISMeF)