Preferred Label : Gallium Ga 68-THP-PSMA;
NCIt synonyms : Gallium Ga 68-labeled THP-PSMA; Gallium Ga 68-Tris(hydroxypyridinone)-Prostate-specific Membrane Antigen; THP-PSMA GA-68; 68GA-THP-PSMA;
NCIt related terms : PSMA-THP GALLIUM GA-68;
NCIt definition : A radioconjugate composed of a human prostate specific membrane antigen (PSMA)-targeting
agent conjugated, via the tris(hydroxypyridinone) (THP) chelator, to the radioisotope
gallium Ga 68, with potential use as a tracer for PSMA-expressing tumors during positron
emission tomography (PET). Upon intravenous administration of the gallium Ga 68-THP-PSMA,
the PSMA moiety targets and binds to PSMA-expressing tumor cells. Upon PET imaging,
PSMA-expressing tumor cells can be detected. PSMA, a tumor-associated antigen (TAA)
and type II transmembrane protein, is expressed on the membrane of prostatic epithelial
cells and overexpressed on prostate tumor cells.;
UNII : JQN3Z29DVH;
NCI Metathesaurus CUI : CL978538;
Origin ID : C165271;
UMLS CUI : C5237043;
Semantic type(s)
- concept_is_in_subset
