Preferred Label : Human Acellular Dermal Matrix;
NCIt synonyms : Human ADM; D-ADM; hADM;
NCIt definition : An allograft composed of sterile, decellularized regenerative human dermal tissue
matrix, with soft tissue reconstructive and transplantation purposes. In this human
acellular dermal matrix (hADM), which is composed of the dermal layer and extracellular
matrix of thin layers of donated skin that have had the epidermal layer removed, the
donor cellular material is removed, which minimizes immunological response in ADM
recipients. The hADM retains native growth factors, collagen and elastin. Using hADM
to support tissue expanders or implants for soft tissue reconstruction or to aid in
wound healing, the matrix allows for rapid cellular proliferation and infiltration,
integration of mesenchymal cells into the matrix and re-vascularization. This facilitates
surgical reconstruction and protects against wound exposure and wound infection.;
Drug name : DermACELL;
NCI Metathesaurus CUI : CL977787;
Origin ID : C164679;
UMLS CUI : C5236479;
Semantic type(s)
- concept_is_in_subset
