Suppression of Tumorigenicity 5 Protein Isoform 3

Preferred Label : Suppression of Tumorigenicity 5 Protein Isoform 3;

NCIt synonyms : DENND2B Isoform 3; p70;

NCIt definition : Suppression of tumorigenicity 5 protein isoform 3 (609 aa, 70 kDa) is encoded by the human DENND2B gene. This protein may play a role in the modulation of cell morphology, cell growth and tumor supression.;

NCIt note : Suppression of tumorigenicity 5 protein isoform 3 is produced by alternative promoter usage and is missing amino acids 1-528, which includes 2 proline-rich regions and the ABL1 interaction domain found in isoform 1. (OMIM and UniProt);

NCI Metathesaurus CUI : CL977353;

Details

Origin ID

C164149;

UMLS CUI

C5236013;

Automatic exact mappings (from CISMeF team)
- Ubiquitin-associated and sh3 domain-containing protein b [OMIM gene]
OMIM relation
- Suppressor of tumorigenicity 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- DENND2B Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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