Suppression of Tumorigenicity 5 Protein Isoform 2

Preferred Label : Suppression of Tumorigenicity 5 Protein Isoform 2;

NCIt synonyms : DENND2B Isoform 2; p82;

NCIt definition : Suppression of tumorigenicity 5 protein isoform 2 (717 aa, 82 kDa) is encoded by the human DENND2B gene. This protein is involved in the activation of Ras-related proteins Rab-9A and Rab-9B.;

NCIt note : Suppression of tumorigenicity 5 protein isoform 2 is produced by alternative splicing of the DENND2B transcript and is missing amino acids 28-447, which includes 2 proline-rich regions and the ABL1 interaction domain found in isoform 1. (OMIM and UniProt);

NCI Metathesaurus CUI : CL977354;

Details

Origin ID

C164148;

UMLS CUI

C5236012;

OMIM relation
- Suppressor of tumorigenicity 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- DENND2B Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients