Alpha-Conotoxin CnIA

Preferred Label : Alpha-Conotoxin CnIA;

NCIt related terms : Alpha-CnIA;

NCIt definition : A 14-amino acid alpha3/5-conotoxin isolated from the venom of the cone snail Conus consors that is a competitive antagonist of the muscle-type nicotinic acetylcholine receptors, blocking synaptic transmission at the neuromuscular junction. Alpha-conotoxins are identified by a characteristic arrangement of four-cysteine residues (-CC-C-C-) and disulfide bonding of Cys1-Cys3 and Cys2-Cys4. In addition, alpha3/5-conotoxins are further classified as having three residues in the first intercysteine loop and five residues in the second intercysteine loop.;

Alternative definition : CDISC: The biotoxin alpha-conotoxin CnIA.;

NCI Metathesaurus CUI : CL976938;

Details

Origin ID

C163580;

UMLS CUI

C0767482;

Automatic exact mappings (from CISMeF team)
- alpha-conotoxin IA [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hazardous or Poisonous Substance [UMLS semantic type]
UMLS correspondences (same concept)
- alpha-conotoxin IA [MeSH Supplementary Concept]
- alpha-conotoxin IA [MeSH concept]
concept_is_in_subset
- CDISC SEND Chemical Challenge Agent Name Response Terminology [NCIt concept]
- CDISC SEND Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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