Cemadotin Hydrochloride

Preferred Label : Cemadotin Hydrochloride;

NCIt synonyms : Cemadotin;

NCIt related terms : LU-103793;

NCIt definition : The hydrochloride salt form of cemadotin, a synthetic dolastatin 15 analogue with potential antineoplastic activity. Cemadotin suppresses spindle microtubule dynamics by binding to tubulin, thereby blocking mitosis. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that reduces the risk of tumor cell growth and reproduction.;

NCIt note : CCR recorded NSC-D-669356;

UNII : 4LJQ1IXS6C;

CAS number : 172837-41-1;

Molecule name : LU-103793;

NSC code : D-669356;

Codes from synonyms : CDR0000045533;

Details

Origin ID

C1634;

UMLS CUI

C1527058;

Automatic exact mappings (from CISMeF team)
- cemadotin [MeSH Supplementary Concept]
- cemadotin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Cemadotin [NCIt concept]
is_salt_form_of
- Cemadotin [NCIt concept]

Keyword's position in hierarchy(ies) :

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