EGFR Exon 20 Tyrosine Kinase Inhibitor Resistant Mutation

Preferred Label : EGFR Exon 20 Tyrosine Kinase Inhibitor Resistant Mutation;

NCIt synonyms : EGFR Exon 20 TKI-Resistant Mutation; ERBB Exon 20 TKI-Resistant Mutation; Epidermal Growth Factor Receptor Gene Exon 20 TKI-Resistant Mutation; ERBB1 Exon 20 TKI-Resistant Mutation; HER1 Exon 20 TKI-Resistant Mutation; EGFR Exon 20 Resistance Mutation;

NCIt definition : A molecular genetic abnormality indicating the presence of secondary mutations in exon 20 of the EGFR gene that result in the translation of an epidermal growth factor receptor protein that is resistant to tyrosine kinase inhibitor therapies.;

NCI Metathesaurus CUI : CL973372;

Details

Origin ID

C163018;

UMLS CUI

C5206890;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
molecular_abnormality_involves_gene
- EGFR Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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