Testicular Signet Ring Stromal Tumor

Preferred Label : Testicular Signet Ring Stromal Tumor;

NCIt synonyms : Primary Signet Ring Stromal Tumor of the Testis; PSRSTT; Testicular Signet-Ring Stromal Tumor;

NCIt definition : An extremely rare tumor that arises from the testis. It is characterized by the proliferation of epithelioid cells with signet ring appearance separated by fibrous tissue into trabeculae and nests. The histologic features are bland and there is no mucin production. Mutations of CTNNB1 gene have been identified in the reported cases. It is considered a special type of sex cord-stromal tumor. All reported cases had a benign clinical course without metastases.;

Neoplastic status : Benign;

NCI Metathesaurus CUI : CL973273;

Details

Origin ID

C162966;

UMLS CUI

C5206868;

Disease excludes abnormal cell
- Neoplastic Germ Cell [NCIt concept]
- Neoplastic Leydig Cell [NCIt concept]
- Neoplastic Sertoli Cell [NCIt concept]
- Neoplastic Sex Cord-Stromal Cell Resembling Steroid Hormone-Secreting Cell [NCIt concept]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Male Reproductive System [NCIt concept]
- Reproductive System [NCIt concept]
- Testis [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Sex Cord-Stromal Cell [NCIt concept]
- Signet Ring Stromal Cell [NCIt concept]
disease_has_molecular_abnormality
- CTNNB1 Gene Mutation [NCIt concept]
disease_has_normal_tissue_origin
- Testicular Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Male Reproductive System [NCIt concept]
- Testis [NCIt concept]

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