Preferred Label : Bifidobacterium longum/Lactobacillus acidophilus/Enterococcus faecalis Probiotic Supplement;
NCIt synonyms : B. longum/L. acidophilus/E. faecalis Probiotic Supplement; Bifidobacterium longum/Lactobacillus acidophilus/Enterococcus faecalis Supplement;
NCIt definition : An orally bioavailable, probiotic supplement containing the microorganisms Bifidobacterium
longum (B. longum), Lactobacillus acidophilus (L. acidophilus) and Enterococcus faecalis
(E. faecalis), with potential immunomodulating, anti-diarrheal and mucosal protective
activities. Upon oral ingestion, the naturally-occurring bacterial components in B.
longum/L. acidophilus/E. faecalis probiotic supplement may improve digestion and help
to maintain adequate colonization of the gastrointestinal (GI) tract by modulating
the composition of the normal microflora. They produce lactic acid, hydrogen peroxide
and other substances during fermentation, thereby creating an acidic environment that
is unfavorable for pathogens. During colonization in the GI tract, the bacteria may
also form a protective intestinal barrier, which may prevent damage to the mucosal
epithelium, maintain the integrity of the epithelial barrier from potential damage
by toxins and certain chemicals, and reduce the potential for attachment of pathogens.
This further protects against bacterial translocation and infection. In addition,
this agent may reduce the secretion of pro-inflammatory cytokines and may potentiate
natural and acquired immunity. Altogether, this may increase immunity, prevent GI
mucosal damage, malabsorption, inflammation, and reduce diarrhea.;
Drug name : Bifico;
NCI Metathesaurus CUI : CL973341;
Origin ID : C162855;
UMLS CUI : C5207036;
Semantic type(s)
concept_is_in_subset