Preferred Label : Personalized Neoantigen Peptide Vaccine iNeo-Vac-P01;
NCIt synonyms : iNeo-Vac-P01;
NCIt definition : A peptide-based, personalized cancer vaccine consisting of patient-specific mutated
long peptides, which are immunogenic and unique to the patient's tumor, with potential
immunomodulating and antineoplastic activities. Upon vaccination with the personalized
neoantigen peptide vaccine iNeo-Vac-P01, the peptides stimulate the host immune system
to mount a specific and potent cytotoxic T-lymphocyte (CTL) response against tumor
cells expressing the neoantigens, which results in tumor cell lysis.;
NCI Metathesaurus CUI : CL971029;
Origin ID : C162633;
UMLS CUI : C5206707;
Semantic type(s)
chemical_or_drug_has_mechanism_of_action
concept_is_in_subset