Uroacitides - CISMeF

Preferred Label : Uroacitides;

NCIt synonyms : CDA-II; Cell Differentiation Agent II;

NCIt definition : A mixture of peptides, organic acids, pigments, and phenylacetylglutamine isolated from healthy human urine with potential antineoplastic activity. Upon administration, uroacitides, also known as cell differentiation agent II (CDA-II) may inhibit telomerase activity in tumor cells. This may lead to an accumulation of tumor cells in G1 phase and inhibition of tumor cell proliferation.;

NCI Metathesaurus CUI : CL971119;

Details

Origin ID

C162545;

UMLS CUI

C5206638;

Automatic exact mappings (from CISMeF team)
- SEC23 homolog B, COPII coat complex component [ORDO Gene]
- cell differentiation agent II [MeSH concept]
- cell differentiation agent II [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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