Tomoregulin-2 - CISMeF

Preferred Label : Tomoregulin-2;

NCIt synonyms : Transmembrane Protein with EGF-Like and Two Follistatin-Like Domains 2; Tomoregulin; Hyperplastic Polyposis Protein 1; Transmembrane Protein with EGF-Like and Two Follistatin-Like Domains; TR-2; TMEFF2; Transmembrane Protein TENB2; Transmembrane Protein with EGF-Like and 2 Follistatin-Like Domains 2;

NCIt definition : Tomoregulin-2 (374 aa, 41 kDa) is encoded by the human TMEFF2 gene. This protein may play a role in the positive regulation of cell growth and cell survival.;

NCIt note : A soluble form of tomoregulin-2 (TMEFF2-ECD) is produced by proteolytic shedding mediated by disintegrin and metalloproteinase domain-containing protein 17 (ADAM17). (UniProt);

Details

Origin ID

C162408;

UMLS CUI

C5202844;

Automatic exact mappings (from CISMeF team)
- Transmembrane protein with egf-like and 2 follistatin-like domains 2 [OMIM gene]
- transmembrane protein with EGF like and two follistatin like domains 2 [HGNC gene]
OMIM relation
- Transmembrane protein with egf-like and 2 follistatin-like domains 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TMEFF2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- EGF-Like Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Migration Inhibition Process [NCIt concept]
- Nerve Cell Survival [NCIt concept]

Keyword's position in hierarchy(ies) :

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