Oncogene CSF1R

Preferred Label : Oncogene CSF1R;

NCIt synonyms : Oncogene FMS;

NCIt definition : Human colony stimulating factor 1 receptor (CSF1R) gene, located at 5q33.2-q33.3, encodes macrophage colony stimulating factor I receptor protein. Mutations in this gene have been detected in both chronic myelomonocytic leukemia and type M4 acute myeloblastic leukemia. One out of fifty hematologically normal individuals exhibit a CSFR1 variant allele (Y969C) that may cause a predisposition to myeloid malignancy.;

GenBank Accession Number : X03663;

Détails

Origin ID

C16240;

UMLS CUI

C0919447;

Automatic exact mappings (from CISMeF team)
- Colony-stimulating factor 1 receptor [OMIM gene]
OMIM relation
- Colony-stimulating factor 1 receptor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Myeloid Leukemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 5q33-q35 [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- Cell Survival [NCIt concept]
- Hematopoietic Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumorigenesis [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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