Detumomab - CISMeF

Preferred Label : Detumomab;

NCIt synonyms : Immunoglobulin G1, Anti-(Human B Lymphoma Cell) (Mouse Monoclonal SPECIFID Heavy Chain), Disulfide with Mouse Monoclonal SPECIFID Light Chain, Dimer;

NCIt definition : A recombinant mouse immunoglobulin G1 (IgG1) monoclonal antibody directed against an undisclosed B-cell lymphoma tumor-associated antigen (TAA), with potential antineoplastic activity. Upon administration, detumomab targets and binds to a TAA expressed on B-cell lymphoma cells. This prevents TAA-mediated signaling and kills the tumor cells.;

UNII : 8Z3Q8X4UAD;

CAS number : 145832-33-3;

NCI Metathesaurus CUI : CL970852;

Details

Origin ID

C162347;

UMLS CUI

C5206542;

Currated CISMeF NLP mapping
- Detumomab [SMS substance]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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