Preferred Label : Tandem Mass Tag;
NCIt synonyms : TMT;
NCIt definition : A group of amine-reactive reagents used as tags for isobaric mass labeling that are
comprised of a mass reporter region (M), a cleavable linker region (F), a mass normalization
region (N) and a protein reactive group (R). Tandem mass tags (TMT) are added to peptides
following sample collection, protein purification and protein digestion. These tags
are identical in chemical composition but isotope substitutions in the M and N regions
allow these regions to have different molecular masses. The number of isotope substitutions
is equal to the number of distinct samples that can be tagged and assayed.;
NCI Metathesaurus CUI : CL970366;
Origin ID : C161866;
UMLS CUI : C5202845;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
