Preferred Label : Arginase-1 Peptide Vaccine;
NCIt synonyms : ARG-1 Peptide Vaccine;
NCIt definition : A vaccine comprised of arginase-1 peptides, with potential antineoplastic activity.
Upon vaccination, the arginase-1 peptide vaccine may activate the immune system to
induce an immune response against arginase-1-expressing cells. Arginase-1 is expressed
by some cancer cells and by immune inhibitory cells, such as myeloid-derived suppressor
cells (MDSCs) and tumor-associated macrophages (TAMs); its expression is associated
with poor prognosis.;
NCI Metathesaurus CUI : CL970399;
Origin ID : C161833;
UMLS CUI : C5206132;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
