" /> BR96-Doxorubicin Immunoconjugate - CISMeF





Preferred Label : BR96-Doxorubicin Immunoconjugate;

NCIt synonyms : BR96-DOX immunoconjugate; BR96-Doxorubicin Conjugate; cBR96-Doxorubicin Immunoconjugate; BR96-DOX; BR96-Doxorubicin;

NCIt definition : An antibody-drug conjugate composed of the chimeric monoclonal antibody BR96 chemically linked to the cytotoxic drug doxorubicin. The antibody moiety of BMS-182248-1 binds to Lewis Y, a cell surface antigen expressed on many solid tumor types. Thus, the doxorubicin conjugate is targeted specifically to Lewis Y-expressing tumor cells, where it intercalates with DNA, thereby inhibiting DNA replication and repair, RNA synthesis and protein synthesis. (NCI);

Molecule name : SGN-15; BMS-182248-01;

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28/07/2025


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