Preferred Label : Bio-enhanced Curcumin Extract Formulation;
NCIt synonyms : BCM95CG; BCM-95 CG Curcumin; BCM-95 CG Curcumin Extract; BCM95 CG; Bio-enhanced BCM-95 CG Curcumin; BCM-95CG; Curcumin BCM-95CG; BCM-95 (R) CG;
NCIt definition : A bio-enhanced extract-based preparation containing curcumin, a poorly water-soluble
phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as
turmeric, with a variety of pharmacologic properties, including antineoplastic, chemopreventive,
antioxidant, anti-angiogenic, neuroprotective and anti-inflammatory activities. Upon
oral administration, curcumin blocks the formation of reactive-oxygen species, neutralizes
free radicals, and prevents oxidative stress and DNA damage. Curcumin also possesses
anti-inflammatory properties as a result of inhibition of cyclooxygenases (COX) and
other enzymes involved in inflammation. It disrupts various cell signal transduction
pathways involved in carcinogenesis and prevents the expression of many transcription
factors. In addition, curcumin modulates phase II enzymes. Altogether, this prevents
and/or inhibits tumor cell formation and proliferation. Compared to the very poorly
absorbed curcumin alone, this extract formulation, by micronizing curcumin and adding
turmeric essential oils, has a much greater bioavailability, an improved pharmacokinetic
profile and increased efficacy.;
Drug name : Biocurcumax;
NCI Metathesaurus CUI : CL970143;
Origin ID : C161600;
UMLS CUI : C5205929;
Semantic type(s)
- concept_is_in_subset
