NCIt definition : A symmetrical dimeric bis-naphthalimide compound and a topoisomerase II inhibitor
with antineoplastic activity. Elinafide contains two neutral chromophores joined by
a cationic linker and is capable of bis-intercalation at the TpG and CpA steps of
the DNA hexanucleotide. Intercalation inhibits topoisomerase II activity and causing
DNA stand breakage, thereby leads to inhibition of DNA, RNA, and protein synthesis.;
Alternative definition : NCI-GLOSS: An anticancer drug that kills cancer cells by affecting DNA synthesis.;
UNII : HL580335SI;
InChIKey : QUNOQBDEVTWCTA-UHFFFAOYSA-N;
CAS number : 162706-37-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 162706-37-8
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