Preferred Label : Oncolytic Virus ASP9801;
NCIt definition : An engineered oncolytic virus with potential antineoplastic and immunomodulating activities.
Upon intratumoral injection of ASP-9801, the oncolytic virus selectively targets and
replicates in cancer cells without being able to infect and replicate in normal, healthy
cells. This induces selective oncolytic virus-mediated cytotoxicity in cancer cells,
which leads to cancer cell lysis. Following the lysis of infected cells, the replicated
virus is released and can infect adjacent tumor cells, which both induces further
tumor cell oncolysis and may activate the immune system to exert an anti-tumor immune
response against the tumor cells.;
Molecule name : ASP-9801; ASP 9801;
NCI Metathesaurus CUI : CL969987;
Origin ID : C161021;
UMLS CUI : C5205725;
Semantic type(s)
- Virus [UMLS semantic type]
- concept_is_in_subset
