Tecogalan Sodium

Preferred Label : Tecogalan Sodium;

NCIt synonyms : Sulfated Polysaccharide Tecogalan DS-4152; SP-PG;

NCIt definition : A sulfated polysaccharide isolated from various Arthrobacter bacterial species. Possessing potential antiangiogenic and antineoplastic properties, tecogalan binds to basic fibroblast growth factor (bFGF), thereby preventing bFGF from binding to its receptors. Disruption of this receptor binding results in the inhibition of bFGF-stimulated endothelial cell growth, proliferation, and migration. (NCI04);

Molecule name : DS-4152;

Details

Origin ID

C1605;

UMLS CUI

C0287957;

Automatic exact mappings (from CISMeF team)
- tecogalan [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- tecogalan sodium [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- tecogalan sodium [MeSH concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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