Preferred Label : Cord Blood-derived CMV/AdV/EBV/BKV-specific Cytotoxic T-lymphocytes;
NCIt synonyms : Cord Blood-derived CMV/AdV/EBV/BKV-specific T-cells; UCB-derived CMV/AdV/EBV/BKV-specific T-cells; Allogeneic Cord Blood-derived CMV/AdV/EBV/BKV-specific CTLs;
NCIt definition : A population of allogeneic expanded cord blood (CB)-derived cytotoxic T-lymphocytes
(CTLs) that are specifically reactive to cytomegalovirus (CMV), Epstein-Barr virus
(EBV), adenovirus (AdV), and human polyomavirus type I (BKV), with potential antiviral
activity. Infusion of the CB-derived CMV/AdV /EBV/BKV-specific CTLs into CB hematopoietic
stem cell transplant (HSCT) recipients may provide virus-specific cellular immunity,
thereby preventing the infection or reactivation of certain viral-associated diseases.;
NCI Metathesaurus CUI : CL969253;
Origin ID : C160294;
UMLS CUI : C5205117;
Semantic type(s)
- Cell [UMLS semantic type]
concept_is_in_subset