NCIt definition : A synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic
androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens.
This agent does not bind to most mutated forms of androgen receptors. (NCI04);
Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called antiandrogens.;