" /> Bicalutamide - CISMeF





Preferred Label : Bicalutamide;

NCIt synonyms : N-[4-Cyano-3-(trifluoromethyl)phenyl]3-3[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-propanamide; ( /-)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide; 4'-Cyano-alpha,alpha,alpha-trifuloro-3-[(p-fluorophenyl)sulfonyl]-2-methyl-m-lactotoluidide; 4-Cyano-3-trifluoromethyl-N-(3-p-fluorophenylsulfonyl-2-hydroxy-2-methylpropionyl)aniline;

NCIt definition : A synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called antiandrogens.;

UNII : A0Z3NAU9DP;

InChIKey : LKJPYSCBVHEWIU-UHFFFAOYSA-N;

CAS number : 90357-06-5;

Drug name : Cosudex; Casodex; Cassotide; Utamide;

Molecule name : ICI 176334; ICI 176,334;

Chemical formula : C18H14F4N2O4S;

NSC code : 722665;

ChEBI ID : CHEBI:3090;

Codes from synonyms : 08923; CDR0000045354; 70;

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25/05/2025


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