" /> Gusperimus Trihydrochloride - CISMeF





Preferred Label : Gusperimus Trihydrochloride;

NCIt synonyms : 1-Amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione; Deoxyspergualin Hydrochloride; 15-Deoxyspergualin; N-[[[4-[(3-Aminopropyl)amino]-butyl]carbamoyl]hydroxymethyl]-7-guanidinoheptanamide; 7-[(Aminoiminomethyl)amino]-N-[2-[[4-[(3-aminopropyl)amino]butyl]amnio]-1-hydroxy-2-oxoethyl]heptanamide; DSG; 15-Deoxyspergualin Hydrochloride; Gusperimus;

NCIt related terms : Deoxyspergualin; ( -)-15-Deoxyspergualin;

NCIt definition : A derivative of the antitumor antibiotic spergualin with immunosuppressant activity. Gusperimus inhibits the interleukin-2-stimulated maturation of T cells to the S and G2/M phases and the polarization of the T cells into IFN-gamma-secreting Th1 effector T cells, resulting in the inhibition of growth of activated naive CD4 T cells; this agent may suppress growth of certain T-cell leukemia cell lines. (NCI04);

UNII : QZS4144IO0;

InChIKey : AXSPHUWXYSZPBG-UHFFFAOYSA-N;

CAS number : 84937-45-1;

Drug name : Spanidin;

Molecule name : BMS-181173; NKT-01; BMY-42215-1;

Chemical formula : C17H37N7O3.3HCl;

NSC code : 356894;

Codes from synonyms : NSC0356894;

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09/05/2025


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