Preferred Label : Recombinant Alpha Chemokine;
NCIt synonyms : C-X-C Chemokines; CXC Chemokines; Alpha Chemokines; CXC alpha Chemokine; Therapeutic Alpha Chemokine;
NCIt definition : One of a number of chemotactic cytokines. Alpha chemokines are small polypeptides
released by macrophages, endothelial cells, keratinocytes, fibroblasts, and smooth
muscle cells in the presence of infection or physical tissue damage. In a therapeutic
setting, these agents may act as chemoattractants to recruit neutrophils and T cells
from the blood to sites of infection or damage and may either promote or inhibit tumor
growth by modulating tumor-associated angiogenesis and metastasis. Also known as CXC
chemokines. (NCI04);
Origin ID : C1592;
UMLS CUI : C1527035;
Currated CISMeF NLP mapping
- Semantic type(s)
