" /> Carbon C 11 Martinostat - CISMeF





Preferred Label : Carbon C 11 Martinostat;

NCIt synonyms : [11C]-metformin; [11C]Martinostat;

NCIt related terms : MARTINOSTAT C-11;

NCIt definition : A radioconjugate composed of martinostat, a histone deacetylase (HDAC) inhibitor, labeled with the positron-emitting isotope carbon C 11, with potential use in imaging via positron emission tomography (PET)/magnetic resonance imaging (MRI). Upon intravenous administration of carbon C 11 martinostat, the martinostat moiety targets and binds to HDAC on tumor cells. Upon PET/MRI imaging, this radioligand may allow for the assessment of HDAC-expressing tumor cells. HDACs, upregulated in many tumor cell types, are a family of metalloenzymes responsible for the deacetylation of chromatin histone proteins.;

UNII : 7LBT5K33WN;

InChIKey : WNIDBXBLQFPAJA-WKEKCCTESA-N;

CAS number : 1629052-59-0;

NCI Metathesaurus CUI : CL951030;

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05/07/2025


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